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Application of the new generation cytogenetics technology in structural variation of leukemia genome / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma ; (12): 197-200, 2021.
Article in Zh | WPRIM | ID: wpr-882263
Responsible library: WPRO
ABSTRACT
Structural variation (SV) of the genome is a group of critical genetic abnormalities in hematological tumors. The currently commonly-used cytogenetics and gene testing techniques have significant limitations in the detection of SV. Genome optical mapping technology provides a powerful tool for analyzing SV with ultra-long fragments, high resolution, automation, high throughput and genome-wide range. It is also known as the next-generation cytogenetics (NGC) technology. In recent years, there have been research reports on the use of NGC for the analysis of SV of leukemia genome. The related research progress is now introduced in conjunction with the reports at the 62nd American Society of Hematology Annual Meeting.
Full text: 1 Index: WPRIM Language: Zh Journal: Journal of Leukemia & Lymphoma Year: 2021 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: Journal of Leukemia & Lymphoma Year: 2021 Type: Article