Relationship between preoperative breast specific gamma imaging tumor/normal take-up ratio and the prognosis of breast cancer / 中华普通外科杂志
Chinese Journal of General Surgery
;
(12): 191-195, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-885274
ABSTRACT
Objective:
To investigate the relationship between T/N take-up value and the clinic feature of breast cancer, and explore the predictive ability of T/N take-up value for breast cancer prognosis.Methods:
Breast cancer patients treated at Zhongshan Hospital, Fudan University and undergoing BSGI examination before surgery from Jan 2014 to Nov 2018 were collected. The relationship between T/N take-up value and the clinical features of breast cancer and DFS was analyzed.Results:
A total of 419 breast cancer patients were collected. The median follow-up time after operation was 34 months. At the end of the follow-up, 43 cases relapsed and 376 cases did not. The average T/N values of CC position and MLO position before surgery were 2.74 and 2.58. The T/N value of CC is related to tumor stage (χ 2=22.077, P<0.05), lymph node metastasis ( Z=2.138, P<0.05) and degree of invasion ( Z=3.371, P<0.05). The T/N value of MLO is related to tumor stage (χ 2=23.091, P<0.05), lymph node metastasis ( Z=2.531, P<0.05) and degree of invasion ( Z=2.99, P<0.05). The best cut-off values of CC position and MLO position calculated by ROC curve are 2.59 and 2.97. Univariate analysis showed that tumor staging ( HR 2.039, 95% CI 1.404-2.962, P=0.001), T/N value at CC position ( HR 4.349, 95% CI 2.141-8.883, P<0.001) and T/N value at MLO position ( HR 2.767, 95% CI 1.520-5.039, P<0.001) is an independent risk factor for the prognosis of breast cancer. Multivariate COX regression analysis showed that tumor stage ( HR 1.959, 95% CI 1.302-2.946, P=0.001) and T/N value at MLO position ( HR 3.498, 95% CI 1.531-7.992, P=0.003) are independent risk factor of breast cancer prognosis.Conclusion:
The BSGI T/N value has a certain correlation with breast cancer DFS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of General Surgery
Year:
2021
Type:
Article
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