Clinical efficacy of Bushen Huoxue Culuan Formula in treatment of infertility caused by diminished ovarian reserve due to kidney deficiency and blood stasis / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2644-2649, 2021.
Article
in Zh
| WPRIM
| ID: wpr-887934
Responsible library:
WPRO
ABSTRACT
To study the clinical efficacy and safety of Bushen Huoxue Culuan Formula in treating infertility caused by diminished ovarian reserve(DOR) with kidney deficiency and blood stasis. A total of 100 DOR patients treated at Xiyuan Hospital, Acupuncture Hospital and Clinic of China Academy of Chinese Medical Sciences from 2017 to 2020 in line with the inclusion criteria were selected and randomly divided into experimental group and control group at the ratio of 1∶1. The experimental group was treated with Bushen Huoxue Culuan Formular, while the control group was treated with Climen and Clomiphene for 3 menstrual cycles. The ovulation rate, pregnancy rate, pregnancy success rate, serum hormone levels, and traditional Chinese medicine(TCM) symptom scores were observed in the 2 groups. The total effective rate was 92.00% in the experimental group and 72.00% in the control group, with a statistical difference between the two groups(P<0.01); the experimental group was superior to the control group in reducing FSH level, increasing AMH level, improving TCM symptoms, increasing pregnancy rate and pregnancy success rate, with a significant difference(P<0.05). There was no abnormal safety indicator and adverse reaction. Bushen Huoxue Culuan Formular is effective in treating infertility caused by DOR due to kidney deficiency and blood stasis, with a safety and reliability.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Drugs, Chinese Herbal
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China
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Reproducibility of Results
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Treatment Outcome
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Ovarian Reserve
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Infertility, Female
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Kidney
Limits:
Female
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Humans
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Pregnancy
Country/Region as subject:
Asia
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2021
Type:
Article