New bisabolane-type phenolic sesquiterpenoids from the marine sponge Plakortis simplex / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 626-631, 2021.
Article
in En
| WPRIM
| ID: wpr-888791
Responsible library:
WPRO
ABSTRACT
Six new bisabolane-type phenolic sesquiterpenoids, including plakordiols A-D (1-4), (7R, 10R)-hydroxycurcudiol (5) and (7R, 10S)-hydroxycurcudiol (6) were isolated from the marine sponge Plakortis simplex collected from the South China Sea. Their structures were determined based on extensive analysis of spectroscopic data. Their configurations were assigned by coupling constant analysis, NOESY correlations, and the modified Mosher's method. Furthermore, their cytotoxic and antibacterial activities were evaluated.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Pacific Ocean
/
Molecular Structure
/
China
/
Plakortis
/
Monocyclic Sesquiterpenes
/
Anti-Bacterial Agents
Limits:
Animals
Country/Region as subject:
Asia
Language:
En
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2021
Type:
Article