Reconstitution of biosynthetic pathway for mushroom-derived cyathane diterpenes in yeast and generation of new "non-natural" analogues | Acta Pharmaceutica Sinica B;(6): 2945-2956, 2021. | WPRIM

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Reconstitution of biosynthetic pathway for mushroom-derived cyathane diterpenes in yeast and generation of new "non-natural" analogues

Ke MA; Yuting ZHANG; Cui GUO; Yanlong YANG; Junjie HAN; Bo YU; Wenbing YIN; Hongwei LIU.

Acta Pharmaceutica Sinica B ; (6): 2945-2956, 2021.

Article in En | WPRIM | ID: wpr-888897

Responsible library: WPRO

ABSTRACT

ABSTRACT

Mushroom-derived cyathane-type diterpenes possess unusual chemical skeleton and diverse bioactivities. To efficiently supply bioactive cyathanes for deep studies and explore their structural diversity,

Key words

Biosynthesis; Cyathane-type diterpene; Heterologous expression; Non-enzymatic reaction

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Full text: 1 Index: WPRIM Language: En Journal: Acta Pharmaceutica Sinica B Year: 2021 Type: Article

Search on Google

Full text: 1 Index: WPRIM Language: En Journal: Acta Pharmaceutica Sinica B Year: 2021 Type: Article