Prescreening skin test effectiveness in predicting hypersensitivity to iodinated contrast media
Journal of the Korean Medical Association
; : 155-158, 2020.
Article
in Ko
| WPRIM
| ID: wpr-893124
Responsible library:
WPRO
ABSTRACT
Hypersensitivity reaction to iodinated contrast media (ICM) is a persistent clinical issue owing to widespread use of computed tomography (CT) examinations. The question of whether routine performance of skin tests can predict hypersensitivity reactions to contrast media remains unresolved. Recently, a prospective study was performed to evaluate the role of an intradermal skin test as a prescreening test for hypersensitivity reactions to ICM. Fifteen (0.5%) of the 2,843 patients had positive skin test results prior to scheduled CT scans. However, none of the patients experienced a hypersensitivity reaction after administration of full-dose ICM. Meanwhile, 19 patients who experienced hypersensitivity reactions to an ICM challenge showed negative skin test results. The sensitivity and positive predictive value of skin tests for hypersensitivity reaction to ICM were both 0%. More studies should be conducted to confirm the uselessness of prescreening skin tests. In conclusion, a prescreening intradermal skin test prior to a CT scan has no significant clinical value as a tool for predicting hypersensitivity reactions to ICM. Therefore, prescreening skin tests should not be routinely performed.
Full text:
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Index:
WPRIM
Type of study:
Observational_studies
/
Prognostic_studies
Language:
Ko
Journal:
Journal of the Korean Medical Association
Year:
2020
Type:
Article