Molecular basis and diagnosis of thalassemia
Blood Research
; : S39-S43, 2021.
Article
in En
| WPRIM
| ID: wpr-897352
Responsible library:
WPRO
ABSTRACT
Thalassemia is characterized by the impaired synthesis of globin chains due to disease-causing variants in α- or β-globin genes. In this review, we provide an overview of the molecular basis underlying α- and β-thalassemia, and of the current technologies used to characterize these disease-causing variants for the diagnosis of thalassemia.Understanding these molecular basis and technologies will prove to be beneficial for the accurate diagnosis of thalassemia.
Full text:
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Index:
WPRIM
Type of study:
Diagnostic_studies
Language:
En
Journal:
Blood Research
Year:
2021
Type:
Article