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The hereditary characteristics and promising therapeutic targets of neuroblastoma / 国际儿科学杂志
Article in Zh | WPRIM | ID: wpr-907247
Responsible library: WPRO
ABSTRACT
Neuroblastoma(NB)has the highest incidence in pediatric extracranial solid tumors, so its pathogenesis is urgently needed to figure out and guide the targeted therapies.Both heterogeneous pathological characteristics and various clinical phenotypes show that NB has cryptic biological and genetic features.This paper reviews the evidence of gene mutations and epigenetic changes in NB to prospect for new therapeutic targets.
Key words
Full text: 1 Index: WPRIM Language: Zh Journal: International Journal of Pediatrics Year: 2021 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: International Journal of Pediatrics Year: 2021 Type: Article