Risk factors of lymph node metastasis in early gastric cancer / 中华普通外科杂志
Chinese Journal of General Surgery
;
(12): 734-738, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-911607
ABSTRACT
Objective:
To investigate the clinical characteristics and risk factors of lymph node metastasis of early gastric cance.Methods:
The data of 176 early gastric cancer patients (EGC) undergoing radical gastrectomy were analyzed retrospectively.Results:
Lymph node (LN) metastasis occurred in 24 patients. The average harvested LN in the negative group was 23±13, and that in the positive group was 30±16, ( t=0.327, P=0.015). Univariate analysis showed that there were significant differences in the depth of tumor invasion ( χ2=3.997, P=0.046), degree of pathological differentiation ( χ2=9.919, P=0.007), vascular invasion ( χ2=35.145, P=0.000) and nerve invasion ( χ2=13.343, P=0.000). Multivariate analysis showed that vascular infiltration ( OR=16.172, 95% CI 4.781-55.875), nerve infiltration ( OR=1.365, 95% CI 1.029-14.897), infiltration depth ( OR=1.859, 95% CI 1.844-22.711) were independent risk factors for LN metastasis in early gastric cancer ( P<0.05). The overall 3-year survival rate was 96.6%, and the 5-year survival rate was 91.6%.Conclusion:
The lymph node metastasis of early gastric cancer is related to the degree of differentiation, the depth of invasion, vascular invasion, nerve invasion and the number of lymph node dissected.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of General Surgery
Year:
2021
Type:
Article
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