Imaging Protocol and Criteria for Evaluation of Axillary Lymph Nodes in the NAUTILUS Trial / 한국유방암학회지
Journal of Breast Cancer
; : 554-560, 2021.
Article
in En
| WPRIM
| ID: wpr-914826
Responsible library:
WPRO
ABSTRACT
Axillary ultrasonography (US) is the most commonly used imaging modality for nodal evaluation in patients with breast cancer. No Axillary Surgical Treatment in Clinically Lymph Node-Negative Patients after Ultrasonography (NAUTILUS) is a prospective, multicenter, randomized controlled trial investigating whether sentinel lymph node biopsy (SLNB) can be safely omitted in patients with clinically and sonographically node-negative T1–2 breast cancer treated with breast-conserving therapy. In this trial, a standardized imaging protocol and criteria were established for the evaluation of axillary lymph nodes. Women lacking palpable lymph nodes underwent axillary US to dismiss suspicious nodal involvement.Patients with a round hypoechoic node with effaced hilum or indistinct margins were excluded. Patients with T1 tumors and a single node with a cortical thickness ≥ 3 mm underwent US-guided biopsy. Finally, patients with negative axillary US findings were included. The NAUTILUS axillary US nodal assessment criteria facilitate the proper selection of candidates who can omit SLNB.
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Index:
WPRIM
Type of study:
Clinical_trials
/
Guideline
Language:
En
Journal:
Journal of Breast Cancer
Year:
2021
Type:
Article