Application of bioisostere-bicyclo [1.1.1] pentane (BCP) in drug design / 中国药科大学学报
Journal of China Pharmaceutical University
; (6): 1-9, 2022.
Article
in Zh
| WPRIM
| ID: wpr-920643
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WPRO
ABSTRACT
@#With the development of medicinal and organic chemistry, more and more classical and non-classical bioisosteres are used in the design of novel drugs.Bicyclo[1.1.1] pentane (BCP), as a bioisostere of benzene, t-butyl and alkyne moieties,has recently received extensive attention from medicinal and organic chemists.This paper briefly reviews its application in drug design to provide reference for drug discovery researchers.
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Language:
Zh
Journal:
Journal of China Pharmaceutical University
Year:
2022
Type:
Article