Progress of researches on anti-infective properties of epigallocatechin-3-gallate / 中国血吸虫病防治杂志

ABSTRACT

(-)-epigallocatechin-3-O-gallate (EGCG) is the most abundant polyphenol in green tea, which has shown anti-oxidant, anti-inflammatory, anti-thrombotic, anti-radiation, anti-mutant, anti-cancer and anti-fibrotic actions, and has shown improvements of diabetes, obesity, asthma, cancer, cardiovascular diseases and central nervous system disorders. In addition, EGCG is reported to enhance the human immunity. Recently, EGCG has been found to play a vital role in infectious diseases caused by pathogenic microorganisms, including bacteria, fungi, viruses and parasites. The review summarizes the progress of researches on anti-infective properties of EGCG, so as to elucidate the potential role of EGCG in the prevention and treatment of infectious diseases.