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Effects of different irradiators on the establishment of osteoradionecrosis model of rat mandible / 华西口腔医学杂志
Article in En | WPRIM | ID: wpr-921369
Responsible library: WPRO
ABSTRACT
OBJECTIVES@#To compare the effects of different irradiators on the establishment of osteoradionecrosis of jaw model (ORNJ) to explore an ideal modeling method.@*METHODS@#A total of 33 adult SD rats were included and randomly divided into three groups according to the radiation equipment, namely, the blank control (CN, 3 rats), group A (linear accelerator irradiation, 15 rats), and group B (small-animal irradiator irradiation, 15 rats). Groups A and B were irradiated with daily fractions of 7, 8, and 9 Gy for 5 days and further divided into three subgroups as follows: group A@*RESULTS@#At 3 weeks after dental extractions, complete gingival healing was found in the regions of dental extractions in groups A@*CONCLUSIONS@#Small-animal irradiator irradiation is an ideal device for establishing ORNJ model.
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Full text: 1 Index: WPRIM Main subject: Osteoradionecrosis / Rats, Sprague-Dawley / X-Ray Microtomography / Mandible / Molar Limits: Animals Language: En Journal: West China Journal of Stomatology Year: 2021 Type: Article
Full text: 1 Index: WPRIM Main subject: Osteoradionecrosis / Rats, Sprague-Dawley / X-Ray Microtomography / Mandible / Molar Limits: Animals Language: En Journal: West China Journal of Stomatology Year: 2021 Type: Article