Application of CRISPR/Cas-based biosensors for detecting nucleic acid of pathogens / 生物工程学报
Chinese Journal of Biotechnology
; (12): 3890-3904, 2021.
Article
in Zh
| WPRIM
| ID: wpr-921474
Responsible library:
WPRO
ABSTRACT
Clustered regularly interspaced short palindromic repeats/clustered regularly interspaced short palindromic repeats -associated protein (CRISPR/Cas) has been developed as a precise, efficient, affordable and sensitive nucleic acid detection tool due to its efficient targeted binding ability and programmability. At present, biosensors based on CRISPR-Cas system have shown excellent performance in the detection of nucleic acid of pathogens, which has attracted widespread attention, and is expected to replace the conventional detection methods. This review summarizes the latest research progress of biosensors based on CRISPR/Cas system for detecting nucleic acid of pathogens.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Nucleic Acids
/
Biosensing Techniques
/
CRISPR-Cas Systems
Language:
Zh
Journal:
Chinese Journal of Biotechnology
Year:
2021
Type:
Article