Effect of lower limb amputation level on aortic hemodynamics: a numerical study / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 67-74, 2022.
Article
in Zh
| WPRIM
| ID: wpr-928200
Responsible library:
WPRO
ABSTRACT
It has been found that the incidence of cardiovascular disease in patients with lower limb amputation is significantly higher than that in normal individuals, but the relationship between lower limb amputation and the episodes of cardiovascular disease has not been studied from the perspective of hemodynamics. In this paper, numerical simulation was used to study the effects of amputation on aortic hemodynamics by changing peripheral impedance and capacitance. The final results showed that after amputation, the aortic blood pressure increased, the time averaged wall shear stress of the infrarenal abdominal aorta decreased and the oscillatory shear index of the left and right sides was asymmetrically distributed, while the time averaged wall shear stress of the iliac artery decreased and the oscillatory shear index increased. The changes above were more significant with the increase of amputation level, which will result in a higher incidence of atherosclerosis and abdominal aortic aneurysm. These findings preliminarily revealed the influence of lower limb amputation on the occurrence of cardiovascular diseases, and provided theoretical guidance for the design of rehabilitation training and the optimization of cardiovascular diseases treatment.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Aorta, Abdominal
/
Stress, Mechanical
/
Blood Flow Velocity
/
Aortic Aneurysm, Abdominal
/
Lower Extremity
/
Hemodynamics
/
Amputation, Surgical
/
Models, Cardiovascular
Type of study:
Guideline
/
Prognostic_studies
Limits:
Humans
Language:
Zh
Journal:
Journal of Biomedical Engineering
Year:
2022
Type:
Article