Upregulation of h-TERT and Ki-67 in ectopic endometrium is associated with recurrence of endometriosis / 浙江大学学报(英文版)(B辑:生物医学和生物技术)
Journal of Zhejiang University. Science. B
;
(12): 158-163, 2022.
Article
in English
| WPRIM
| ID: wpr-929047
ABSTRACT
At present, endometriosis remains a worldwide health burden, with the main symptoms of dysmenorrhea, chronic pelvic pain, and infertility, markedly reducing the quality of life (de Ziegler et al., 2010). Although there is no proof that the disease is associated with high mortality, this disorder can significantly contribute to the deterioration of women's general well-being (McPeak et al., 2018). The main current treatment for endometriosis is surgery to remove endometriotic lesions; however, the recurrence rate following surgical treatment is as high as 21.5% at two years and 40.0%-50.0% at five years post-surgery (Koga et al., 2015). To prevent recurrence, adjuvant treatment with drugs after surgery is recommended to prolong relapse-free intervals. However, it is inconvenient for patients to continuously use such medications in terms of adverse effects and cost (Turk, 2002).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality of Life
/
Recurrence
/
Up-Regulation
/
Telomerase
/
Ki-67 Antigen
/
Endometriosis
/
Endometrium
Limits:
Female
/
Humans
Language:
English
Journal:
Journal of Zhejiang University. Science. B
Year:
2022
Type:
Article
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