Your browser doesn't support javascript.
loading
New anti-pulmonary fibrosis prenylflavonoid glycosides from Epimedium koreanum / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.) ; (6): 221-228, 2022.
Article in English | WPRIM | ID: wpr-929255
ABSTRACT
Four new prenylflavonoid glycosides, namely koreanoside H-K (1-4), together with eleven known ones (5-15) were isolated from the leaves of Epimedium koreanum Nakai. Their structures were elucidated by 1D NMR, 2D NMR, HR-ESI-MS, IR and UV. The identification of the sugar moieties was carried out by means of acid hydrolysis and HPLC analysis of their derivatives. It is worth noting that compound 3 and compound 4 were elucidated to contain fucose and quinovose moieties, which were two extremely rare sugar units from the genus Epimedium. The anti-pulmonary fibrosis activity of the new compounds was evaluated using A549 cell line. Compounds 1, 2 and 4 showed significant anti-pulmonary fibrosis activities.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Plant Extracts / Chromatography, High Pressure Liquid / Plant Leaves / Epimedium / Glycosides Language: English Journal: Chinese Journal of Natural Medicines (English Ed.) Year: 2022 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Plant Extracts / Chromatography, High Pressure Liquid / Plant Leaves / Epimedium / Glycosides Language: English Journal: Chinese Journal of Natural Medicines (English Ed.) Year: 2022 Type: Article