Progress on the gene polymorphism and prolonged neonatal jaundice / 国际儿科学杂志

ABSTRACT

Some children with neonatal jaundice may have prolonged neonatal jaundice, and the regression of jaundice is delayed for 2~3 months.The severe complication is nuclear jaundice, which is manifested as irreversible nervous system damage.Therefore, neonatal jaundice has become an important global concern problem.At present, the pathogenesis of prolonged neonatal jaundice is not clear.Recent studies have found that genetic factors are closely related to prolonged neonatal jaundice.In this review, the research progress of common gene polymorphism and prolonged neonatal jaundice are summarized.