Research advances on signaling pathways affecting sweat gland development and their involvement in the reconstitution of sweat adenoid cells in vitro / 中华烧伤杂志
Chinese Journal of Burns
; (6): 195-200, 2022.
Article
in Zh
| WPRIM
| ID: wpr-935995
Responsible library:
WPRO
ABSTRACT
The damage of sweat glands in patients with extensive deep burns results in the loss of thermoregulation, which seriously affects the quality of life of patients. At present, there are many researches on the repair of sweat gland function, but the mechanism of human sweat gland development has not been fully clarified. More and more studies have shown that the cascaded pathways of Wnt/β-catenin, ecto- dysplasin A/ectodysplasin A receptor/nuclear factor-κB, sonic hedgehog, and forkhead box transcription factor jointly affect the development of sweat glands, and it has been reported that the cascaded signaling pathways can be used to achieve the reconstruction of sweat adenoid cells in vitro. This article reviews the signaling pathways that affect the development of sweat glands and their involvement in the reconstruction of sweat adenoid cells in vitro.
Full text:
1
Index:
WPRIM
Main subject:
Quality of Life
/
Sweat
/
Sweat Glands
/
Signal Transduction
/
Adenoids
/
Hedgehog Proteins
Limits:
Humans
Language:
Zh
Journal:
Chinese Journal of Burns
Year:
2022
Type:
Article