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Progress and prospect of application of traditional Chinese medicine fingerprint (specific chromatogram) in Chinese Pharmacopoeia (2010-2020) / 南方医科大学学报
Journal of Southern Medical University ; (12): 150-155, 2022.
Article in Chinese | WPRIM | ID: wpr-936297
ABSTRACT
The Chinese Pharmacopoeia began to apply fingerprints (specific chromatogram) to quality control of traditional Chinese medicine in its 2010 edition, and in its 2015 and 2020 editions, new fingerprints (specific chromatogram) were added for improvement of the Pharmacopoeia-based national standards for drugs. This review analyzes the traditional Chinese medicine fingerprints (specific chromatogram) in Chinese Pharmacopoeia (2010-2020) in terms of the number of varieties listed, application of fingerprints (specific chromatogram), selection of evaluation method, determination method, the selection of extraction or preparation solvents of the test samples. With the expansion of the application of fingerprints (specific chromatogram), the evaluation indicators are constantly improving. The future development of the fingerprints (specific chromatogram) is also discussed in light of the selection of appropriate extraction or preparation solvents to obtain effective substances, which is the basis for the establishment of the fingerprints; multiple fingerprints for one drug based on different functional indications or basic sources, which expands the application of the fingerprints; addition of technical guidelines for traditional Chinese medicine fingerprints to standardize the use of the fingerprints; and the regular revision, update and application expansion of the fingerprints to ensure its essential role in quality control of traditional Chinese medicine.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Quality Control / Solvents / Drugs, Chinese Herbal / China / Chromatography, High Pressure Liquid / Medicine, Chinese Traditional Type of study: Diagnostic study Country/Region as subject: Asia Language: Chinese Journal: Journal of Southern Medical University Year: 2022 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Quality Control / Solvents / Drugs, Chinese Herbal / China / Chromatography, High Pressure Liquid / Medicine, Chinese Traditional Type of study: Diagnostic study Country/Region as subject: Asia Language: Chinese Journal: Journal of Southern Medical University Year: 2022 Type: Article