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A Case of Pleomorphic Dermal Sarcoma and Literature Review according to World Health Organization Reclassification Guideline / 대한피부과학회지
Article in En | WPRIM | ID: wpr-938499
Responsible library: WPRO
ABSTRACT
Pleomorphic dermal sarcoma (PDS), formerly known as malignant fibrous histiocytoma (MFH), is a rare mesenchymal tissue tumor. A 40-year-old male presented with a 2-month history of a well-defined, solitary, round, palpable protruding mass with central ulceration, 1.5 cm in diameter. Punch biopsy showed tumor cells of variable size and hyperchromatic nuclei with frequent bizarre atypical cells and atypical mitoses arranged in a storiform-pleomorphic pattern in the entire dermis. After complete resection, PDS was diagnosed because the lesion had invaded the deep subcutaneous fat. Because MFH has been renamed according to the World Health Organization new classification system, we reclassified the 10 cases that have been reported as MFH in Korea. Nine cases were renamed undifferentiated pleomorphic sarcoma, with only one being renamed mucofibrosarcoma. Herein, we report a rare case of PDS treated with surgical excision with a review of the literature.
Full text: 1 Index: WPRIM Type of study: Guideline Language: En Journal: Korean Journal of Dermatology Year: 2022 Type: Article
Full text: 1 Index: WPRIM Type of study: Guideline Language: En Journal: Korean Journal of Dermatology Year: 2022 Type: Article