Role of inflammation in intracranial aneurysms and potential drug therapy / 国际脑血管病杂志

ABSTRACT

Intracranial aneurysm is a common cerebrovascular disease, which has a high morbidity and mortality after rupture, usually resulting in poor prognosis. Intracranial aneurysms are mainly treated by craniotomy clipping and endovascular embolization, but there is still controversy about whether the unruptured aneurysms with a diameter of <5 mm need intervention. Studies have shown that inflammation plays an important role in the formation, progression, and rupture of intracranial aneurysms. Aspirin and statins can delay the development of intracranial aneurysms and help reduce the risk of rupture through anti-inflammatory. This article reviews the inflammatory mechanism and potential drug therapy of intracranial aneurysms.