Ischemic Colitis Caused by Terlipressin during Treatment of Hepatorenal Syndrome / 대한내과학회지
Korean Journal of Medicine
;
: 406-409, 2016.
Article
in Korean
| WPRIM
| ID: wpr-96327
ABSTRACT
Terlipressin, a vasopressin agonist, is widely used to treat variceal bleeding and hepatorenal syndrome in patients with liver cirrhosis. Terlipressin increases systemic vascular resistance, particularly in the splanchnic area, thus decreasing portal pressure. Although terlipressin is associated with a lower incidence of severe cardiovascular complications than is vasopressin, terlipressin can induce serious ischemic complications including myocardial infarction, skin necrosis, and bowel ischemia in < 1% of patients. We report the case of a 79-year-old female with liver cirrhosis treated with terlipressin to control hepatorenal syndrome that developed into ischemic colitis. The patient improved upon cessation of terlipressin and provision of supportive care.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Vascular Resistance
/
Hepatorenal Syndrome
/
Vasopressins
/
Esophageal and Gastric Varices
/
Incidence
/
Portal Pressure
/
Colitis, Ischemic
/
Ischemia
/
Liver Cirrhosis
Type of study:
Incidence study
/
Prognostic study
Limits:
Aged
/
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2016
Type:
Article
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