Outbreaks of mumps: an observational study over two decades in a single hospital in Korea / 소아과
Korean Journal of Pediatrics
; : 396-402, 2014.
Article
in En
| WPRIM
| ID: wpr-96678
Responsible library:
WPRO
ABSTRACT
PURPOSE:
The introduction of the mumps vaccine has dramatically reduced the number of mumps cases, but outbreaks have recently occurred among highly vaccinated populations in developed countries. Epidemiological and clinical characteristics of patients with mumps admitted between 1989 and 2012 in a single hospital in Korea are described in the present study.METHODS:
We retrospectively evaluated inpatients with mumps between 1989 and 2012 and outpatients and inpatients with mumps in 2011-2012.RESULTS:
A total of 152 patients with mumps were admitted between 1989 and 2012, and 163 patients were recorded in 2011-2012. The highest number of admitted cases occurred in 1998 and 2012 (35 and 34 cases, respectively). Among the patients admitted in 2011-2012, the highest frequency was observed among people aged 15-19 years, and low frequency was observed in those aged 20 years, compatible to the city data and national data. In patients admitted to our department in 1998 (35 cases) and in 2010-2012 (27 cases), there were significant differences in the mean age and the rate of secondary measles-mumps-rubella (MMR) vaccination, but had similar clinical features, including complications, except aseptic meningitis. Antimumps immunoglobulin (Ig) G was positive in 83% and 100%, and IgM was positive in 67% and 41%, respectively, in the two periods.CONCLUSION:
In Korea, recent mumps outbreaks have occurred mainly among secondary school students who received two doses of the MMR vaccine. The vaccinees might have a modified immune reaction to viral insults, manifesting modified epidemiological and clinical features.Key words
Full text:
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Index:
WPRIM
Main subject:
Outpatients
/
Immunoglobulin M
/
Immunoglobulins
/
Mumps Vaccine
/
Developed Countries
/
Disease Outbreaks
/
Retrospective Studies
/
Vaccination
/
Measles-Mumps-Rubella Vaccine
/
Observational Study
Type of study:
Observational_studies
Limits:
Humans
Country/Region as subject:
Asia
Language:
En
Journal:
Korean Journal of Pediatrics
Year:
2014
Type:
Article