Seven-Year Clinical Outcomes of Sirolimus-Eluting Stent Versus Bare-Metal Stent: A Matched Analysis From A Real World, Single Center Registry
Journal of Korean Medical Science
; : 396-401, 2013.
Article
in En
| WPRIM
| ID: wpr-98487
Responsible library:
WPRO
ABSTRACT
The aim of this study is to compare clinical outcomes for seven years, between sirolimus-eluting stent (SES) and bare metal stent (BMS). During the BMS and drug-eluting stent (DES) transition period (from April 2002 to April 2004), 434 consecutive patients with 482 lesions underwent percutaneous coronary intervention, using BMS or SES. Using propensity score matching, 186 patients with BMS and 166 patients with SES were selected. Seven year clinical outcomes of major adverse cardiac events (MACE), such as cardiac death, myocardial infarction (MI) and ischemia-driven target vessel revascularization (TVR), and angiographic definite stent thrombosis (ST) were compared. At one-year follow up, patients with SES showed significantly lower MACE (9.1% in BMS vs 3.0% in SES, P = 0.024). However, cumulative MACE for 7 yr was not significantly different between two groups (24.7% in BMS vs 17.4% in SES, P = 0.155). There was no significant difference in MI, TVR, death and ST. The TVR were gradually increased from 1 to 7 yr in SES, on the contrary to that of BMS. In conclusion, although SES showed better clinical outcomes in the early period after implantation, it did not show significant benefits in the long-term follow up, compared with that of BMS.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Thrombosis
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Angioplasty, Balloon, Coronary
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Stents
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Registries
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Follow-Up Studies
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Databases, Factual
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Coronary Angiography
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Sirolimus
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Coronary Stenosis
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Kaplan-Meier Estimate
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Aged
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Female
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Humans
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Male
Language:
En
Journal:
Journal of Korean Medical Science
Year:
2013
Type:
Article