Research Progress on MicroRNA in Forensic Medicine as Molecular Markers / 法医学杂志
Journal of Forensic Medicine
; (6): 374-378, 2020.
Article
in En
| WPRIM
| ID: wpr-985129
Responsible library:
WPRO
ABSTRACT
MicroRNA (miRNA) belongs to a class of endogenous non-coding small RNA molecules with a length of 18-24 nucleotides. The expression of miRNA is highly conservative, has time sequence and is highly tissue-specific. MiRNA could not be easily degraded by ribonuclease, and is resistant to changes in environmental factors such as temperature and pH value. Moreover, miRNA can even be detected in corrupt tissue. As a result, miRNA has broad application prospects in many fields of forensic medicine such as source identification of body fluid and estimation of cause of death. This article briefly summarizes the application of miRNA in forensic practice, such as body fluid identification, determination of postmortem interval and cause of death analysis.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Genetic Markers
/
MicroRNAs
/
Forensic Genetics
/
Forensic Medicine
Limits:
Humans
Language:
En
Journal:
Journal of Forensic Medicine
Year:
2020
Type:
Article