Survey of prevalence of hepatitis C in people aged 1-69 years in Henan Province, 2020 / 中华流行病学杂志
Chinese Journal of Epidemiology
; (12): 1114-1118, 2023.
Article
in Zh
| WPRIM
| ID: wpr-985641
Responsible library:
WPRO
ABSTRACT
Objective:
To understand the infection status and epidemiological characteristics of hepatitis C in people aged 1-69 years in Henan Province in 2020.Methods:
The estimated sample size was 5 827. From August to December 2020, multistage sampling was used to select 8 counties (districts) in Henan, and two survey sites were selected in each county (district), and a questionnaire survey was conducted in local people aged 1-69 years, blood samples were collected from them for anti-HCV, HCV RNA and genotype detections.Results:
A total of 5 165 people aged 1-69 years completed the questionnaire survey. Men accounted for 44.76% (2 312/5 165), women accounted for 55.24% (2 853/5 165). In the people aged 1-69 years, the overall prevalence rates of anti-HCV and HCV RNA were 0.69% (95%CI 0.68%-0.70%) and 0.20% (95%CI 0.19%-0.21%) respectively. The prevalence rates of anti-HCV and HCV RNA were 0.48% (95%CI 0.46%-0.50%), 0.09% (95%CI 0.08%-0.10%) in men and 0.86% (95%CI 0.85%-0.87%), 0.30% (95%CI 0.28%-0.32%) in women. The prevalence rates of anti-HCV and HCV RNA increased with age. The prevalence rates of anti-HCV and HCV RNA were 0.87% (95%CI 0.86%-0.88%), 0.28% (95%CI 0.26%-0.30%) in urban residents and 0.53% (95%CI 0.51%-0.55%), 0.14% (95%CI 0.13%-0.15%) in rural residents. The genotyping results of 10 HCV RNA positive samples ware genotype 1b (4/10), genotype 2 (3/10), genotype 1b/3 (1/10), genotype 1b/3/6 (1/10) and genotype 2/6 (1/10).Conclusions:
The prevalence of hepatitis C was low in Henan in 2020. It is necessary to strengthen hepatitis C surveillance in people aged 40 years and above. The major HCV genotypes were 1b and 2, and mixed genotype infection existed.
Full text:
1
Index:
WPRIM
Main subject:
RNA, Viral
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Prevalence
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Surveys and Questionnaires
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Hepatitis C
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Hepacivirus
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Hepatitis C Antibodies
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Coinfection
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Genotype
Limits:
Adolescent
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Adult
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Aged
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Language:
Zh
Journal:
Chinese Journal of Epidemiology
Year:
2023
Type:
Article