Research progress of tripartite motif-containing protein 28 in tumors / 中国医师杂志
Journal of Chinese Physician
; (12): 630-633, 2023.
Article
in Zh
| WPRIM
| ID: wpr-992348
Responsible library:
WPRO
ABSTRACT
Tripartite motif-containing protein 28 is a kind of macromolecular protein with E3 ubiquitin ligase, which belongs to an important member of the TRIM protein family. As a new molecular biomarker, it has attracted wide attention. TRIM28 is highly expressed in many kinds of malignant tumors, which is closely related to clinicopathological features, and is also involved in biological behaviors such as proliferation, apoptosis, migration and invasion of tumor cells. TRIM28 may be a potential marker and therapeutic target for clinical diagnosis and prognosis of tumors. This study reviews the structure and biological function of TRIM28, its relationship with malignant tumors and the molecular mechanism of signal transduction pathway.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Journal of Chinese Physician
Year:
2023
Type:
Article