Intravoxel Incoherent Motion MR Imaging in the Head and Neck: Correlation with Dynamic Contrast-Enhanced MR Imaging and Diffusion-Weighted Imaging
Korean Journal of Radiology
; : 641-649, 2016.
Article
in En
| WPRIM
| ID: wpr-99439
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To investigate the correlation between perfusion- and diffusion-related parameters from intravoxel incoherent motion (IVIM) and those from dynamic contrast-enhanced MR imaging (DCE-MRI) and diffusion-weighted imaging in tumors and normal muscles of the head and neck. MATERIALS ANDMETHODS:
We retrospectively enrolled 20 consecutive patients with head and neck tumors with MR imaging performed using a 3T MR scanner. Tissue diffusivity (D), pseudo-diffusion coefficient (D*), and perfusion fraction (f) were derived from bi-exponential fitting of IVIM data obtained with 14 different b-values in three orthogonal directions. We investigated the correlation between D, f, and D* and model-free parameters from the DCE-MRI (wash-in, Tmax, Emax, initial AUC60, whole AUC) and the apparent diffusion coefficient (ADC) value in the tumor and normal masseter muscle using a whole volume-of-interest approach. Pearson's correlation test was used for statistical analysis.RESULTS:
No correlation was found between f or D* and any of the parameters from the DCE-MRI in all patients or in patients with squamous cell carcinoma (p > 0.05). The ADC was significantly correlated with D values in the tumors (p 0.05, respectively).CONCLUSION:
Intravoxel incoherent motion shows no significant correlation with model-free perfusion parameters derived from the DCE-MRI but is feasible for the analysis of diffusivity in both tumors and normal muscles of the head and neck.Key words
Full text:
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Index:
WPRIM
Main subject:
Perfusion
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Magnetic Resonance Imaging
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Carcinoma, Squamous Cell
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Retrospective Studies
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Diffusion
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Head
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Masseter Muscle
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Muscles
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Neck
Type of study:
Observational_studies
Limits:
Humans
Language:
En
Journal:
Korean Journal of Radiology
Year:
2016
Type:
Article