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Intravoxel Incoherent Motion MR Imaging in the Head and Neck: Correlation with Dynamic Contrast-Enhanced MR Imaging and Diffusion-Weighted Imaging
Article in En | WPRIM | ID: wpr-99439
Responsible library: WPRO
ABSTRACT

OBJECTIVE:

To investigate the correlation between perfusion- and diffusion-related parameters from intravoxel incoherent motion (IVIM) and those from dynamic contrast-enhanced MR imaging (DCE-MRI) and diffusion-weighted imaging in tumors and normal muscles of the head and neck. MATERIALS AND

METHODS:

We retrospectively enrolled 20 consecutive patients with head and neck tumors with MR imaging performed using a 3T MR scanner. Tissue diffusivity (D), pseudo-diffusion coefficient (D*), and perfusion fraction (f) were derived from bi-exponential fitting of IVIM data obtained with 14 different b-values in three orthogonal directions. We investigated the correlation between D, f, and D* and model-free parameters from the DCE-MRI (wash-in, Tmax, Emax, initial AUC60, whole AUC) and the apparent diffusion coefficient (ADC) value in the tumor and normal masseter muscle using a whole volume-of-interest approach. Pearson's correlation test was used for statistical analysis.

RESULTS:

No correlation was found between f or D* and any of the parameters from the DCE-MRI in all patients or in patients with squamous cell carcinoma (p > 0.05). The ADC was significantly correlated with D values in the tumors (p 0.05, respectively).

CONCLUSION:

Intravoxel incoherent motion shows no significant correlation with model-free perfusion parameters derived from the DCE-MRI but is feasible for the analysis of diffusivity in both tumors and normal muscles of the head and neck.
Subject(s)
Key words
Full text: 1 Index: WPRIM Main subject: Perfusion / Magnetic Resonance Imaging / Carcinoma, Squamous Cell / Retrospective Studies / Diffusion / Head / Masseter Muscle / Muscles / Neck Type of study: Observational_studies Limits: Humans Language: En Journal: Korean Journal of Radiology Year: 2016 Type: Article
Full text: 1 Index: WPRIM Main subject: Perfusion / Magnetic Resonance Imaging / Carcinoma, Squamous Cell / Retrospective Studies / Diffusion / Head / Masseter Muscle / Muscles / Neck Type of study: Observational_studies Limits: Humans Language: En Journal: Korean Journal of Radiology Year: 2016 Type: Article