Application progress of microfluidic chip in isolation and capture of circulating tumor cells / 中华检验医学杂志

ABSTRACT

The amount of circulating tumor cells(CTC) in peripheral blood is very small, which is difficult to isolate. Microfluidic chips are becoming a hot area in recent years because of their portability, high sensitivity, high capture,and low cost. Microfluidic devices have been shown to maintain optimal performance for CTC isolation capture, including flux, purity, recovery, and clinical relevance. However, microfluidic technology is still unable to recover CTC with high recovery and purity.