Role of neurotransmitters in the pathogenesis of myopia / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
; (12): 1816-1820, 2023.
Article
in Zh
| WPRIM
| ID: wpr-996890
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WPRO
ABSTRACT
With complex pathogenesis, myopia is a common ophthalmology disease and a major causation for visual impairment in children. For years, studies found that neurotransmitters, such as dopamine, nitric oxide, acetylcholine, γ-aminobutyric acid, 5-hydroxytryptamine, insulin and prostaglandins, are associated with children's refractive development and axial length growth. However, there are still many disagreements in their mechanisms of action. This article makes a systematic review on the roles of neurotransmitters in the pathogenesis of myopia including neurotransmitter receptors and antagonists to clarify the influence of different neurotransmitters on the occurrence and development of myopia, thus giving a comprehensive insight into its pathogenesis, building a basis for further research on the changes of neurotransmitters and providing new ideas and directions for the prevention and treatment of myopia.
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WPRIM
Language:
Zh
Journal:
International Eye Science
Year:
2023
Type:
Article