A rare case of multiple pituitary adenomas in an adolescent Cushing disease presenting as a vertebral compression fracture
Annals of Pediatric Endocrinology & Metabolism
; : 197-202, 2017.
Article
in En
| WPRIM
| ID: wpr-99766
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ABSTRACT
Cushing disease in children and adolescents, especially with multiple pituitary adenomas (MPAs), is very rare. We report 17-year-old boy with MPAs. He presented with a vertebral compression fracture, weight gain, short stature, headache, and hypertension. On magnetic resonance imaging (MRI), only a left pituitary microadenoma was found. After surgery, transient clinical improvement was observed but headache and hypertension were observed again after 3 months later. Follow-up MRI showed a newly developed right pituitary microadenoma 6 months after the surgery. The need for careful clinical and radiographic follow-up should be emphasized in the search for potential MPAs in patients with persistent Cushing disease.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Pituitary Neoplasms
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Magnetic Resonance Imaging
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Weight Gain
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Follow-Up Studies
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Pituitary ACTH Hypersecretion
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Fractures, Compression
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Headache
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Hypertension
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Adolescent
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Child
/
Humans
/
Male
Language:
En
Journal:
Annals of Pediatric Endocrinology & Metabolism
Year:
2017
Type:
Article