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Structural insights into SARS-CoV-2 infection and therapeutics development.
Sun, Gangyu; Xue, Lulu; He, Qingjing; Zhao, Yue; Xu, Wenqing; Wang, Zhizhi.
  • Sun G; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Xue L; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • He Q; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Zhao Y; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Xu W; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
  • Wang Z; School of Life Science and Technology, ShanghaiTech University, Shanghai, China. Electronic address: wangzhzh@shanghaitech.edu.cn.
Stem Cell Res ; 52: 102219, 2021 04.
Article in English | MEDLINE | ID: covidwho-1062599
ABSTRACT
The current COVID-19 pandemic is caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). By late October 2020, more than 43 million cases of infections, including over 1.15 million deaths, have been confirmed worldwide. This review focuses on our current understanding of SARS-CoV-2 from the perspective of the three-dimensional (3D) structures of SARS-CoV-2 viral proteins and their implications on therapeutics development against COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / COVID-19 Drug Treatment Type of study: Observational study Limits: Humans Language: English Journal: Stem Cell Res Year: 2021 Document Type: Article Affiliation country: J.scr.2021.102219

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / COVID-19 Drug Treatment Type of study: Observational study Limits: Humans Language: English Journal: Stem Cell Res Year: 2021 Document Type: Article Affiliation country: J.scr.2021.102219