Clinical characteristics of 228 hospitalized patients with COVID-19
Medical Journal of Wuhan University
; 42(5):709-713, 2021.
Article
in Chinese
| Scopus | ID: covidwho-1350548
ABSTRACT
Objective:
To describe the epidemiological and clinical features of coronavious disease 2019 (COVID-19).Methods:
The data of 228 inpatients diagnosed as COVID-19 in the Third Hospital of Wuhan from January 27, 2020, to February 29, 2020 were collected, and their clinical characteristics and outcomes were analyzed.Results:
The average age of inpatients was 58 years old. Common symptoms included fever (88.2%), fatigue (69.7%), and dry cough (59.2%). There were patients with gastrointestinal discomfort as the first symptom (7.9%). In severe patients, lymphocytes decreased significantly, albumin decreased, D-dimer increased, lactate dehydrogenase and creatine kinase isoenzyme increased (all P <0.05). Chest CT of all patients showed patchy shadows or frosted glass opacity of both lungs. Severe patients were more likely to have comorbidities ( P <0.05), and more likely to have complications including acute respiratory distress syndrome (ARDS) (19 cases, 8.3%), arrhythmia (13 cases, 5.7%), and shock (5 cases, 2.2%), and 7% COVID⁃19 cases were transferred to the ICU due to the worsening of the disease, and the patients' mortality rate was 4.4%. There were no specific drugs for treatment, and supportive treatment was the mainstay.Conclusion:
Severe patients had differences in age of onset, underlying diseases, symptoms, laboratory tests, and complications, etc., and needed to be identified earlier. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Type of study:
Prognostic study
Language:
Chinese
Journal:
Medical Journal of Wuhan University
Year:
2021
Document Type:
Article
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