Post covid fatal antibody dependent enhancement of dengue infection in a young male: Double trouble

ABSTRACT

Antibodies against Dengue virus (DENV) have been postulated to act against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2) which might reduce the severity of COVID19 in a patient who previously had dengue fever. However, we report a case of 30 year old male who presented with dengue shock syndrome two months after contracting COVID19. The patient had no history of dengue fever in the past and had no IgG antibodies against Dengue Virus whereas he tested positive for IgG SARS CoV 2 antibodies. Therefore, we highlight a rare case of Antibody Dependent Enhancement of Dengue fever as a result of antibodies against SARS CoV2 in a young male which proved to be fatal. In our knowledge this is the first case in the world to report dengue shock syndrome as a result of SARS CoV2 antibodies.