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Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword.
Abdessamad, Hilal W; Achkar, Michel; Al Zoghbi, Amal; Fleifel, Mohamad; Ousta, Abdul Rahman; Kassar, Ahmad; Samaha, Nadia L; Nemr, Rita; Farra, Anna; Mokhbat, Jacques E; Husni, Rola.
  • Abdessamad HW; Infectious Diseases, Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
  • Achkar M; Internal Medicine, Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
  • Al Zoghbi A; Endocrinology, Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
  • Fleifel M; Internal Medicine, Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
  • Ousta AR; Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
  • Kassar A; Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
  • Samaha NL; Georgetown University School of Medicine, Washington DC, United States.
  • Nemr R; Endocrinology, Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
  • Farra A; Infectious Diseases, Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
  • Mokhbat JE; Infectious Diseases, Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
  • Husni R; Infectious Diseases, Lebanese American University School of Medicine and Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon.
J Infect Dev Ctries ; 17(5): 623-630, 2023 05 31.
Article in English | MEDLINE | ID: covidwho-20231690
ABSTRACT
Cryptococcal meningitis is an opportunistic infection associated with altered immunity. Immunomodulatory agent use in severe coronavirus disease 2019 (COVID-19) may predispose such infections. Here, we present a 75-year-old male patient who presented with fever and altered general status after severe COVID-19 infection and developed cryptococcal meningitis. Opportunistic infection may arise from the use of immunomodulation in severe COVID-19, especially in the elderly population. This article describes the case and extensively reviews cryptococcal disease post-COVID-19 literature, highlighting the risk from immunosuppressive treatment.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Opportunistic Infections / Meningitis, Cryptococcal / Cryptococcus neoformans / COVID-19 Type of study: Case report / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Aged / Humans / Male Language: English Journal: J Infect Dev Ctries Journal subject: Communicable Diseases Year: 2023 Document Type: Article Affiliation country: Jidc.17170

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Opportunistic Infections / Meningitis, Cryptococcal / Cryptococcus neoformans / COVID-19 Type of study: Case report / Diagnostic study / Observational study / Prognostic study Topics: Long Covid Limits: Aged / Humans / Male Language: English Journal: J Infect Dev Ctries Journal subject: Communicable Diseases Year: 2023 Document Type: Article Affiliation country: Jidc.17170