Brixia score as predictor of D-Dimer levels of COVID-19 patients in intensive care unit
Indonesian Journal of Medicine
; 8(1):92-99, 2023.
Article
in English
| GIM | ID: covidwho-20231806
ABSTRACT
Background:
COVID-19 is caused by a novel virus that can cause lung abnormalities which can be measured with new chest x-ray scoring system named Brixia score. In COVID-19 patients, coagulation disorders are often found that can be seen through D-Dimer levels. This study aimed to prove the Brixia Score as a predictor of D-Dimer levels. Subjects andMethod:
This study was an observational analytic study with a cross-sectional approach. The subjects were 94 COVID-19 patients which taken from ICU Melati 1 Dr. Moewardi General Hospital, Surakarta from March 2021 to August 2021 who met the exclusion and inclusion criteria. The independent variable is the Brixia score performed by radiologists and the dependent variable is D-Dimer levels taken from laboratory results. Sampling was obtained by purposive sampling and the data were investigated using the receiver operating characteristic (ROC) curve.Results:
94 samples were obtained for analysis. The average Brixia Score of patients with D-Dimer <2 micro g/mL was Mean= 15.85;SD= 1.43 and D-Dimer 2 micro g/mL was Mean= 17.29;SD= 0.96. There was a significant difference between the Brixia Score of patients with D-Dimer <2 micro g/mL and D-Dimer 2 micro g/mL (p<0.001). Analysis with the ROC curve shows an area under the curve (AUC) of 0.793. The optimal cutoff value of the Brixia Score for predicting D-Dimer levels was 16.5 (sensitivity 77.9%, specificity 73.1%).Conclusion:
Brixia Score proved to be a predictor of D-Dimer levels of COVID-19 patients in ICU care.
viral diseases; coronavirus disease 2019; human diseases; patients; intensive care units; lungs; intensive care; observational studies; cross-sectional studies; Severe acute respiratory syndrome coronavirus 2; man; Indonesia; Severe acute respiratory syndrome-related coronavirus; Betacoronavirus; Coronavirinae; Coronaviridae; Nidovirales; positive-sense ssRNA Viruses; ssRNA Viruses; RNA Viruses; viruses; Homo; Hominidae; primates; mammals; vertebrates; Chordata; animals; eukaryotes; APEC countries; ASEAN Countries; high Human Development Index countries; lower-middle income countries; South East Asia; Asia; SARS-CoV-2; viral infections; critical care
Full text:
Available
Collection:
Databases of international organizations
Database:
GIM
Type of study:
Observational study
/
Prognostic study
/
Randomized controlled trials
Language:
English
Journal:
Indonesian Journal of Medicine
Year:
2023
Document Type:
Article
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