Botulinum toxin injections during the COVID-19 epidemic: A retrospective chart review
Annals of Movement Disorders
; 6(1):13-16, 2023.
Article
in English
| EMBASE | ID: covidwho-20240316
ABSTRACT
BACKGROUND AND AIM:
Clinical services were severely affected globally during the COVID-19 pandemic. This study aimed to characterize the clinical experience of using botulinum toxin (BTX) injections during the COVID-19 pandemic. Method(s) This is a retrospective chart review of patients who received BTX injections from April 2019 to January 2022. Result(s) A total of 105 patients received an BTX injections, out of which 76 (72.4%) were men. The mean age of the patients was 47.9 +/- 15.1 years. The most common indication for receiving BTX injections was dystonia (n = 79;75.2%), followed by hemifacial spasm (n = 22;21%) and miscellaneous movement disorders (n = 4;3.8%). Focal dystonia (n = 45;57%) was the most frequent form of dystonia, followed by segmental dystonia (n = 24;30%). The percentage of generalized dystonia and hemidystonia was 12% and 1%, respectively. Cervical dystonia (44.4%), blepharospasm (17.8%), and writer's cramp (15.6%) were the most frequent forms of focal dystonia. The miscellaneous group included four patients (3.8%) with trigeminal neuralgia, Holmes tremor, dystonic tics, and hemimasticatory spasm. The mean ages of patients in the dystonia, hemifacial spasm, and the miscellaneous groups were 47.7 +/- 14.9 years, 49.2 +/- 14.0 years, and 44.2 +/- 26.0 years, respectively. The mean BTX dose was 131.6 +/- 104.1 U. The mean BTX doses for the dystonia group, hemifacial spasm, and the miscellaneous group were 158.7 +/- 105.3 U, 40.1 +/- 11.3 U, and 100.0 +/- 70.7 U, respectively. Conclusion(s) Most patients in our cohort had dystonia, followed by hemifacial spasm. Among the patients with dystonia, most had focal dystonia, with cervical dystonia being the most common movement disorder. The data obtained in our study is important to increase awareness of the effectiveness of BTX injections in patients with chronic disorders.Copyright © 2023 Annals of Movement Disorders.
Botulinum toxin; covid-19; dystonia; hemifacial spasm; movement disorder; adult; apraxia of eyelid opening/dt [Drug Therapy]; article; blepharospasm/dt [Drug Therapy]; cervical dystonia/dt [Drug Therapy]; cohort analysis; coronavirus disease 2019; dystonia/dt [Drug Therapy]; epidemic; female; focal dystonia/dt [Drug Therapy]; focal hand dystonia/dt [Drug Therapy]; generalized dystonia/dt [Drug Therapy]; hemidystonia/dt [Drug Therapy]; hemifacial spasm/dt [Drug Therapy]; human; male; middle aged; motor dysfunction/dt [Drug Therapy]; muscle spasm/dt [Drug Therapy]; oromandibular dystonia/dt [Drug Therapy]; pandemic; retrospective study; segmental dystonia/dt [Drug Therapy]; tic/dt [Drug Therapy]; tremor/dt [Drug Therapy]; trigeminus neuralgia/dt [Drug Therapy]; writer's cramp/dt [Drug Therapy]; botulinum toxin A/dt [Drug Therapy]; craniocervical dystonia/dt [Drug Therapy]; hemimasticatory spasm/dt [Drug Therapy]; lingual dystonia/dt [Drug Therapy]
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Language:
English
Journal:
Annals of Movement Disorders
Year:
2023
Document Type:
Article
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