SARS-CoV-2 Receptors and Their Involvement in Cell Infection.

Avdonin, P P; Rybakova, E Yu; Trufanov, S K; Avdonin, P V

Avdonin, P P; Rybakova, E Yu; Trufanov, S K; Avdonin, P V.

Avdonin PP; N.K. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Rybakova EY; N.K. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Trufanov SK; N.K. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Avdonin PV; N.K. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, Russia.

Biochem (Mosc) Suppl Ser A Membr Cell Biol ; 17(1): 1-11, 2023.

Article in English | MEDLINE | ID: covidwho-2250574

ABSTRACT

ABSTRACT

The new coronavirus infection (COVID-19) pandemic caused by SARS-CoV-2 has many times surpassed the epidemics caused by SARS-CoV and MERS-CoV. The reason for this was the presence of sites in the protein sequence of SARS-CoV-2 that provide interaction with a broader range of receptor proteins on the host cell surface. In this review, we consider both already known receptors common to SARS-CoV and SARS-CoV-2 and new receptors specific to SARS-CoV-2.

Keywords

ACE2; ASGR1; CD147; CD209; GRP78; KREMEN1; SARS-CoV-2; cathepsin L; coronavirus; furin; heparan sulfate; neuropilin; receptors; tyrosine protein kinase AXL

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Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Biochem (Mosc) Suppl Ser A Membr Cell Biol Year: 2023 Document Type: Article Affiliation country: S1990747822060034

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