Your browser doesn't support javascript.
Hospital Clonal Outbreak of Fluconazole-Resistant Candida parapsilosis Harboring the Y132F ERG11p Substitution in a French Intensive Care Unit.
Presente, Simona; Bonnal, Christine; Normand, Anne-Cécile; Gaudonnet, Yannick; Fekkar, Arnaud; Timsit, Jean-François; Kernéis, Solen.
  • Presente S; Medical and infectious diseases ICU, APHP, Bichat hospital, Paris, France.
  • Bonnal C; Laboratoire de parasitologie mycologie, AP-HP, Hôpital Bichat Claude Bernard, Paris, France.
  • Normand AC; Laboratoire de parasitologie mycologie, AP-HP, Hôpital Pitié Salpêtrière, Paris, France.
  • Gaudonnet Y; Equipe de Prévention du Risque Infectieux, AP-HP, Hôpital Bichat, Paris, France.
  • Fekkar A; Laboratoire de parasitologie mycologie, AP-HP, Hôpital Pitié Salpêtrière, Paris, France.
  • Timsit JF; Medical and infectious diseases ICU, APHP, Bichat hospital, Paris, France.
  • Kernéis S; Université Paris Cité, INSERM, IAME, Paris, France.
Antimicrob Agents Chemother ; 67(3): e0113022, 2023 03 16.
Article in English | MEDLINE | ID: covidwho-2302042
ABSTRACT
We report the first identification of a fluconazole-resistant Candida parapsilosis (FR-Cp) strain in our hospital, which subsequently caused an outbreak involving 17 patients (12 deaths) within a 26-bed French intensive care unit. Microsatellite genotyping confirmed that all FR-Cp isolates belonged to the same clone. Given recent reports of rapid dissemination of these emerging clones, routine testing of azole susceptibility for all Candida parapsilosis isolates should be encouraged, at least in ICU patients.
Subject(s)
Keywords
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Fluconazole / Candida parapsilosis Limits: Humans Language: English Journal: Antimicrob Agents Chemother Year: 2023 Document Type: Article Affiliation country: Aac.01130-22

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
PubMed Links
Search on Google

Full text: Available Collection: International databases Database: MEDLINE Main subject: Fluconazole / Candida parapsilosis Limits: Humans Language: English Journal: Antimicrob Agents Chemother Year: 2023 Document Type: Article Affiliation country: Aac.01130-22