Assuntos
Fármacos Anti-HIV/efeitos adversos , Infecções por HIV/complicações , HIV-1 , Síndrome Inflamatória da Reconstituição Imune/etiologia , Hanseníase Dimorfa/complicações , Hanseníase Virchowiana/complicações , Corticosteroides/uso terapêutico , Adulto , Fármacos Anti-HIV/uso terapêutico , Dapsona/administração & dosagem , Dapsona/uso terapêutico , Erros de Diagnóstico , Feminino , Infecções por HIV/tratamento farmacológico , Humanos , Lamivudina/administração & dosagem , Lamivudina/efeitos adversos , Lamivudina/uso terapêutico , Hansenostáticos/administração & dosagem , Hansenostáticos/uso terapêutico , Hanseníase Dimorfa/diagnóstico , Hanseníase Dimorfa/tratamento farmacológico , Hanseníase Dimorfa/imunologia , Hanseníase Virchowiana/diagnóstico , Hanseníase Virchowiana/tratamento farmacológico , Hanseníase Virchowiana/imunologia , Neurite (Inflamação)/etiologia , Nevirapina/administração & dosagem , Nevirapina/efeitos adversos , Nevirapina/uso terapêutico , Rifampina/administração & dosagem , Rifampina/uso terapêutico , Senegal , Estavudina/administração & dosagem , Estavudina/efeitos adversos , Estavudina/uso terapêutico , Tinha do Couro Cabeludo/diagnósticoRESUMO
UNLABELLED: The authors had for aim to assess the epidemiology of leprosy in Senegal after 7 years of efficient prevention. METHODS: A retrospective study was made on epidemiologic data in Senegal collected between January 1 and December 31, 2002. The indicators of eradication (total number of new cases diagnosed in that year compared to the country's population, expressed in cases per 100,00 inhabitants), the coverage rate (number of cases treated compared to the number of patients recorded for treatment), as well as the cure rate (percentage of patients having complied to the duration of treatment) were all noted. RESULTS: The mean detection rate was 0.5 case per 100,000 inhabitants with 434 new cases reported. The prevalence rate was 0.99 per 10,000 with 981 cases recorded for total management. The coverage rate for total management was 100%. The observed cure rate was 89% and 8% of the patients were lost to follow-up.
Assuntos
Hanseníase/epidemiologia , Demografia , Humanos , Incidência , Hanseníase/tratamento farmacológico , Hanseníase/prevenção & controle , Prevalência , Estudos Retrospectivos , Senegal/epidemiologia , Resultado do TratamentoRESUMO
Erythema nodosum leprosum (ENL) is an immunological reaction corresponding to vascularitis due to circulating immune complexes usually occurring during treatment of lepromatous leprosy. The precise mechanism underlying ENL are unclear but involvement of tumor necrosis factor alpha (TNFalpha) is suspected. Based on this suspicion pentoxifylline has been used instead of conventional treatments such as corticosteroids and thalidomide.