RESUMO
Three diseases representative of specific health conditions affecting the Southeast Asian refugees living in middle Tennessee are leprosy (chronic bacterial infections), liver fluke infection (parasitic diseases), and hemoglobin E-beta-thalassemia (hematologic disorders). In this paper we discuss incidence, causative agent, mode of transmission, metabolic abnormalities, and management of these conditions.
Assuntos
Doenças Hematológicas/diagnóstico , Enteropatias Parasitárias/diagnóstico , Hanseníase/diagnóstico , Refugiados , Sudeste Asiático/etnologia , Dapsona/uso terapêutico , Quimioterapia Combinada , Feminino , Doenças Hematológicas/complicações , Hemoglobina E , Humanos , Recém-Nascido , Enteropatias Parasitárias/tratamento farmacológico , Laos/etnologia , Hanseníase/tratamento farmacológico , Masculino , Mebendazol/administração & dosagem , Pessoa de Meia-Idade , Niclosamida/administração & dosagem , Gravidez , Complicações Infecciosas na Gravidez/parasitologia , Esplenectomia , Tennessee , Talassemia/complicações , Talassemia/diagnóstico , Tuberculose Cutânea/diagnóstico , Tuberculose Cutânea/tratamento farmacológicoRESUMO
A patient with the acquired immunodeficiency syndrome was found to have a continuous bacillemia of Mycobacterium avium-intracellulare by examination of Kinyoun-stained buffy coat smears. There were 29 cells/cu mm that contained acid-fast bacilli (AFB) and 1.5 X 10(5) AFB/ml of whole blood. The cells of the reticuloendothelial system were engorged with AFB, suggesting reticuloendothelial saturation. The peripheral blood involvement and magnitude of the mycobacterial burden are analogous to leprosy, and it is suggested that other similarities between the immunobiology of leprosy and disseminated M avium-intracellulare infection in the acquired immunodeficiency syndrome may exist.