RESUMO
Significant rise in serum LH and FSH and a fall in serum testosterone have been reported in lepromatous leprosy (Dash, Samuel, Kaur, Datta and Rastogi 1978). This is consistent with extensive damage to the tubular and interstitial cells of the testes (Grabstald and Swan 1952; Desican and Job 1972; Bernard and Veraquez 1973; Samuel, Kumar, Kaur, Kannan, Dash, Rastogi and Datta 1978).
Assuntos
Masculino , Humanos , Adulto , Hanseníase/sangue , Hormônio Foliculoestimulante/sangue , Hormônio Liberador de Gonadotropina , Hormônio Luteinizante/sangueRESUMO
Impotency, sterility, loss of libido, loss of sexual hair and gynecomastia are well documented in patients suffering from leprosy. They occur with greater frequency in lepromatous leprosy as compared to dimorphous and tuberculois types.
Assuntos
Masculino , Humanos , Disfunção Erétil/etiologia , Ginecomastia/fisiopatologia , Hanseníase/fisiopatologia , Hormônio Foliculoestimulante/sangue , Infertilidade Masculina/etiologia , Testículo/fisiopatologia , Testículo/patologiaRESUMO
Twenty six patients of different types of leprosy were studied for radio active iodine uptake (I131) and serum levels of triiodothyronine (T3), thyroxine (T4) and thyroid stimulating hormone (TSH). None of the patients had clinical evidence of thyroid involvement. No significant difference was found between the values obtained in patients and normals and in different varieties of leprosy.
Assuntos
Hanseníase/fisiopatologia , Testes de Função Tireóidea , Glândula Tireoide/fisiopatologia , Feminino , Humanos , Radioisótopos do Iodo , Hanseníase/sangue , Masculino , Tireotropina/sangue , Tiroxina/sangue , Tri-Iodotironina/sangueRESUMO
Open thyroid biopsies from seven patients of bacilliferous leprosy were studied for leprous granuloma or amyloid deposition. None of the patients had clinical evidence of thyroid involvement. Histopathology did not reveal any specific abnormality.
Assuntos
Hanseníase/patologia , Glândula Tireoide/patologia , Biópsia , HumanosRESUMO
Sera from twenty six patients of various types of leprosy were tested for the detection of circulating auto-antibodies and nuclear components against thyroid using various methods. Four patients of lepromatous leprosy had higher levels of thyroid auto-antibodies by latex agglutination. Three patients showed the presence of anti-nuclear antibodies, two belonged to the TT and one to the LL group.