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2.
Probl Tuberk ; (8): 49-51, 2001.
Artigo em Russo | MEDLINE | ID: mdl-11767394

RESUMO

The antigenic structure of M. leprae and M. lufu was comparatively studied for the first time. M. lufu was found to have M. leprae-specific protein with a molecular weight of 36 kDa. M. leprae and M. lufu were similar in their fractional composition of proteins and an antibody response to determinants with equal molecular weights in patients with different forms of leprosy and its varying severity. The findings may improve a diagnostic system in leprosy by using M. lufu antigens as an alternative.


Assuntos
Antígenos de Bactérias/análise , Hanseníase/microbiologia , Mycobacterium leprae/imunologia , Mycobacterium/imunologia , Meios de Cultura , Dapsona/farmacologia , Eletroforese , Humanos , Immunoblotting , Hansenostáticos/farmacologia , Hanseníase/tratamento farmacológico , Peso Molecular , Mycobacterium/efeitos dos fármacos , Mycobacterium/isolamento & purificação , Mycobacterium leprae/efeitos dos fármacos , Mycobacterium leprae/isolamento & purificação
3.
Probl Tuberk ; (5): 49-52, 2000.
Artigo em Russo | MEDLINE | ID: mdl-11077855

RESUMO

The paper presents the results of studied of cultural biochemical and immunochemical properties of the cultured mycobacteria isolated from patients with leprous lesions of (M.01, M.011) and the soil (M. lufu) in compared to other well-known mycobacteria and between them. M.01, M.011, and M. lufu differ from other representatives of the genus Mycobacterium, but they are close to each other in their cultural biochemical and immunochemical properties, antigenic composition, and protein spectra. The findings are an additional characteristic of the biological properties of M.01, M.011, and M. lufu.


Assuntos
Hanseníase/microbiologia , Mycobacterium leprae/isolamento & purificação , Mycobacterium/isolamento & purificação , Microbiologia do Solo , Animais , Antígenos de Bactérias/análise , Meios de Cultura , Resistência Microbiana a Medicamentos , Cobaias , Humanos , Imunoquímica , Mycobacterium/efeitos dos fármacos , Mycobacterium/crescimento & desenvolvimento , Mycobacterium/imunologia , Mycobacterium/metabolismo , Mycobacterium leprae/efeitos dos fármacos , Mycobacterium leprae/crescimento & desenvolvimento , Mycobacterium leprae/imunologia , Mycobacterium leprae/metabolismo
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