RESUMO
Leprosy is an ancient disease that has survived into the modern ages despite an intense effort to eliminate it worldwide. Here we report a case of a 32-year-old woman who had recurrent painful nodules of six months duration. Because of a lack of lesions suggestive of leprosy, she was initially diagnosed to have cutaneous vasculitis and erythema nodosum. However, because of the persistent nature of her condition she was later detected to have leprosy and erythema nodosum leprosum (ENL) with the aid of simple diagnostic tests.
Assuntos
Hanseníase Multibacilar/patologia , Adulto , Eritema/etiologia , Eritema/patologia , Feminino , Humanos , Hanseníase Multibacilar/complicaçõesAssuntos
Imunofluorescência/métodos , Doenças do Sistema Imunitário/diagnóstico , Dermatopatias/diagnóstico , Anticorpos , Complemento C3/imunologia , Técnica Direta de Fluorescência para Anticorpo , Técnica Indireta de Fluorescência para Anticorpo/métodos , Humanos , Imunoglobulina G/sangue , Líquen Plano/diagnóstico , Pênfigo/sangue , Pênfigo/diagnósticoRESUMO
Erythema nodosum leprosum (ENL) or Type-2 Lepra reaction is a manifestation of type III hypersensitivity response and usually occurs in certain cases of lepromatous and borderline lepromatous leprosy. It is usually generalized and evanescent, and responds well to oral corticosteroid therapy. Here we report an unusual case of persistent and localized ENL in a 19-year-old girl, which could be diagnosed with the aid of skin biopsy and histopathological examination.
Assuntos
Eritema Nodoso/patologia , Hanseníase Dimorfa/complicações , Hanseníase Virchowiana/patologia , Corticosteroides/uso terapêutico , Adulto , Quimioterapia Combinada , Eritema Nodoso/tratamento farmacológico , Eritema Nodoso/etiologia , Feminino , Humanos , Hanseníase Virchowiana/tratamento farmacológico , Hanseníase Virchowiana/etiologia , Pele/patologiaRESUMO
Epithelioid sarcoma is an uncommon slow-growing soft tissue malignancy, associated with a high incidence of local recurrence and metastasis. We report a 26-year-old male with epithelioid sarcoma on the right palm with a long history of over seven years, which was initially misdiagnosed as cutaneous tuberculosis and epithelioid hemangioendothelioma, as a result of which the treatment was delayed. No metastasis was found in our patient. The patient was referred to the oncology centre where he underwent wide excision of the lesion followed by radiotherapy. The review of the literature including clinical and histological differential diagnosis is presented as it mimics inflammatory, benign tumors as well as other malignant conditions.