[Leprosy in Lome, Togo: retrospective study of 383 cases]. / Lèpre à Lomé (Togo): étude rétrospective de 383 cas.

The goal of this study was to determine the therapeutic outcomes and clinical forms of leprosy diagnosed in Lomé, Togo. This retrospective study was carried out in leprosy patients managed at the National Center of Dermatology in Lomé between January 1990 and December 2005. During the study period, 383 cases of leprosy were recorded including 366 new cases. The annual diagnosis rate was 23 cases per year. Mean patient age was 35.6 +/- 15.4 years. The proportion of patients in the 15 to 49-year-old bracket and in the under-15-year-old bracket was 75% and 6,4% respectively. Male-to-female ratio was 1.36. Prevalence dropped from 4.4/100,000 inhabitants in 1990 to 1.9/100,000 inhabitants in 2005. The detection rate decreased from 6.8/100,000 inhabitants in 1990 to 2.1/100,000 inhabitants in 2005. There was a high prevalence of multibacillary cases after 1995. The incidence of the leprous reactions was 11%. The infirmity rate was 8.5%. The cure rate was 78% after multidrug therapy in 98.2% of cases. Relapse occurred in 6.1% of cases and 16% were lost from follow-up. This study confirms the decreasing prevalence of leprosy in Lomé as well as its changing clinical profile with an increase in multibacillary leprosy.

[Non-tumor dermatoses diagnosed in the pathologic anatomy laboratory of the Tokoin University hospital center, Lomé (Togo)]. / Les dermatoses non tumorales diagnostiquées dans le laboratoire d'anatomie pathologique du CHU Tokoin, Lomé (Togo).

The non-tumorous skin diseases are common in hospital consultation in tropical countries. These infections constitute a great health problem in black Africa. Their diagnosis is often clinically easy, but sometimes histologically examination is necessary to have the positive diagnosis. In Togo, a retrospective study conducted during ten years, allowed to note 516 cases of non-tumoural dermatosis which were histologically diagnosed. The principal infections were: inflammatory dermatosis 339 cases (213 cases were not specific against 108 specific cases predominated by leprosy: 82 cases), epidermal dermatosis (97 cases, predominated by eczema and psoriasis), dermal lesions (44 cases), lesions of dermic and epidermic junction (23 cases), hypodermic (13 cases). The results of this study shows the diversity of non-tumorous dermatosis diagnosed by the histology. The eradication of these diseases in Africa needs to have efficient laboratory diagnosis and research means in every country.