1.
Carbohydr Res
; 465: 10-15, 2018 07 30.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29879545
RESUMO
The efficient synthesis of a linear pentasaccharide with the structure 1, ß-D-Araf-(1â¯ââ¯2)-α-D-Araf-(1â¯ââ¯5)-α-D-Araf-(1â¯ââ¯5)-α-D-Araf-(1â¯ââ¯5)-α-D-Araf-(1 â 5), as its octyl glycoside has been achieved through a convergent [3 + 2] coupling strategy. The difficult-to-obtain 1,2-cis-ß-arabinofuranosidic bond at the non-reducing end of the target molecule was stereoselectively constructed by the use of a 2-quinolinecarbonyl-directed 1,2-cis glycosylation method.