1.
Indian J Dermatol Venereol Leprol
; 81(1): 43-5, 2015.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25566896
RESUMO
Allopurinol, a drug commonly used for treating gout and hyperuricemia, is a frequent cause of drug eruptions. Recent investigations suggest that HLA-BFNx015801 allele is a very strong marker for allopurinol-induced cutaneous adverse drug reactions (cADRs). In this article we report two cases of allopurinol-induced drug eruptions in patients carrying the HLA-BFNx015801 allele and review the literature on the association between HLA-BFNx015801 and allopurinol-induced cADRs based on a MEDLINE and PubMed search.
Assuntos
Alopurinol/efeitos adversos , Toxidermias/etiologia , Supressores da Gota/efeitos adversos , Antígenos HLA-B/genética , Idoso , Alelos , Toxidermias/genética , Humanos , Masculino , Pessoa de Meia-Idade
2.
Indian J Dermatol Venereol Leprol
; 78(2): 197-9, 2012.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22421658