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1.
Lepr Rev ; 77(3): 219-24, 2006 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-17172002

RESUMO

This study investigates the relapse rate among multibacillary leprosy patients treated with 24 months of MDT in south west China. A retrospective relapse survey was conducted in the southwest of China. A detailed questionnaire was designed to collect the data on relapse among MB patients who completed 2 years of the WHO/MB regimen, from 1989 to 2000. The data about 2517 multibacillary leprosy patients in 27 counties in the southwest of China were collected. Among 2517 MB patients, 235 patients died or were lost to follow-up and 2374 were followed up for more than 3 years after completion of MDT. The total duration of follow-up was 20,825 person-years, with a mean duration of 8.27 years per patient. Five patients with relapse were identified with an accumulated relapse rate of 0.21/1000 person-years. Their initial BIs ranged from 1.8 to 5. The patients with relapse occurred 48-158 months after the completion of MDT. The relapse rate of MB patients treated with 24 months of the WHO/MB regimen was observed to be very low after long-term follow-up.


Assuntos
Farmacorresistência Bacteriana Múltipla , Hansenostáticos/uso terapêutico , Hanseníase/tratamento farmacológico , Hanseníase/epidemiologia , China/epidemiologia , Feminino , Humanos , Hanseníase/etiologia , Masculino , Prontuários Médicos , Prevalência , Recidiva , Estudos Retrospectivos , Inquéritos e Questionários
2.
Fontilles, Rev. leprol ; 25(6): 529-536, sept.-dic. 2006. ilus, tab
Artigo em Es | IBECS | ID: ibc-71507

RESUMO

Este estudio evalúa el índice de recidivas entre los pacientes de lepra tratados con 24 meses de MDT en el suroeste de China. Para ello se llevó a cabo un estudio retrospectivo de recidivas en esta parte del país. Se diseñó un cuestionario muy detallado para recoger los datos sobre las recidivas entre pacientes MB que habían completado 2 años de tratamiento OMS/MB desde 1989 a 2000. Los datos se obtuvieron sobre 2.517 pacientes multibacilares en 27 países del suroeste de China. Entre los 2.517 pacientes MB, 235 pacientes fallecieron o se dieron de baja durante el seguimiento y 2.374 fueron controlados durante más de 3 años después de completar la MDT. La duración total del seguimiento fue de 20,825 personas-año, con una duración media de 8.27 años por paciente. Se identificaron cinco pacientes con recidivas con un índice acumulado de recidivas de 0-21/1.000 personas-año. Los IB iníciales variaron entre 1.8 a 5. Las recidivas se presentaron entre 48-158 mese después de completar la MDT. El índice de recidivas de los pacientes MB tratados con 24 meses con una pauta OMS/MB se consideró muy bajo después de un largo período de seguimiento


This study investigates the relapse rate among multibacillary leprosy patients treated with 24 months of MDT in south west China. A retrospective relapse survey was conducted in the southwest of China. A detailed questionnaire was designed to collect the data on relapse among MB patients who completed 2 years of the WHO/MB regimen, from 1989 to 2000. The data about 2.517 multibacillary leprosy patients in 27 counties in the southwest of China were collected. Among 2.517 MB patients, 235 patients died or were lost to follow-up and 2.374 were followed up for more than 3 years after completion of MDT. The total duration of follow-up was 20,825 person-years, with a mean duration of 8.27 years per patient. Five patients with relapse were identified with an accumulated relapse rate of 0.21-/1.000 person-years. Their initial Bls ranged from 1.8 to 5. The patients with relapse occurred 48-158 months after the completion of MDT. The relapse rate of MB patients treated with 24 months of the WHO/MB regimen was observed to be very low after long-term follow-up


Assuntos
Humanos , Masculino , Feminino , Inquéritos e Questionários , Hanseníase/epidemiologia , Hanseníase/prevenção & controle , Recidiva , Monitoramento Epidemiológico , Inquéritos e Questionários/normas , Estudos Retrospectivos , China/epidemiologia
3.
Fontilles, Rev. leprol ; 25(6): 529-536, sept.-dic. 2006. tab
Artigo em Espanhol | IBECS | ID: ibc-77929

RESUMO

Este estudio evalúa el índice de recidivas entre los pacientes de lepra tratados con 24 meses de MDT en el suroeste de China. Para ello se llevó a cabo un estudio retrospectivo de recidivas en esta parte del país. Se diseñó un cuestionario muy detallado para recoger los datos sobre las recidivas entre pacientes MB que habían completado 2 años de tratamiento OMS/MB desde 1989 a 2000. Los datos se obtuvieron sobre 2.517 pacientes multibacilares en 27 países del suroeste de China. Entre los 2.517 pacientes MB, 235 pacientes fallecieron o se dieron de baja durante el seguimiento y 2.374 fueron controlados durante más de 3 años después de completar la MDT. La duración total del seguimiento fue de 20,825 personas-año, con una duración media de 8.27 años por paciente. Se identificaron cinco pacientes con recidivas con un índice acumulado de recidivas de 0-21/1.000 personas-año. Los IB iníciales variaron entre 1.8 a 5. Las recidivas se presentaron entre 48-158 mese después de completar la MDT. El índice de recidivas de los pacientes MB tratados con 24 meses con una pauta OMS/MB se consideró muy bajo después de un largo período de seguimiento (AU)


This study investigates the relapse rate among multibacillary leprosy patients treated with 24 months of MDT in south west China. A retrospective relapse survey was conducted in the southwest of China. A detailed questionnaire was designed to collect the data on relapse among MB patients who completed 2 years of the WHO/MB regimen, from 1989 to 2000. The data about 2.517 multibacillary leprosy patients in 27 counties in the southwest of China were collected. Among 2.517 MB patients, 235 patients died or were lost to follow-up and 2.374 were followed up for more than 3 years after completion of MDT. The total duration of follow-up was 20,825 person-years, with a mean duration of 8.27 years per patient. Five patients with relapse were identified with an accumulated relapse rate of 0.21-/1.000 person-years. Their initial Bls ranged from 1.8 to 5. The patients with relapse occurred 48-158 months after the completion of MDT. The relapse rate of MB patients treated with 24 months of the WHO/MB regimen was observed to be very low after long-term follow-up (AU)


Assuntos
Humanos , Hansenostáticos/uso terapêutico , Hanseníase/tratamento farmacológico , Seguimentos , Quimioterapia Combinada , Recidiva , China
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