Assuntos
Braço , Neoplasias , Masculino , Pessoa de Meia-Idade , Humanos , Braço/patologia , Neoplasias/patologiaRESUMO
We present a patient with new-onset erythema nodosum leprosum months after successful treatment of her mid-borderline leprosy, which was likely triggered by a combination of antecedent influenza vaccination and upper respiratory tract infection.
Assuntos
Eritema Nodoso , Vacinas contra Influenza/efeitos adversos , Hanseníase Virchowiana , Infecções Respiratórias/complicações , Adulto , Braço/patologia , Feminino , Humanos , Hanseníase Dimorfa , Pele/patologiaAssuntos
Cicatriz/diagnóstico , Anormalidades da Pele/diagnóstico , Dermatopatias/diagnóstico , Cicatrização , Braço/patologia , Criança , Pré-Escolar , Cicatriz/etiologia , Feminino , Mãos/patologia , Humanos , Perna (Membro)/patologia , Masculino , Anormalidades da Pele/complicações , Dermatopatias/complicações , Dermatopatias Vesiculobolhosas/complicações , Dermatopatias Vesiculobolhosas/diagnóstico , Cicatrização/fisiologiaRESUMO
Natural killer/T-cell lymphoma is a rare, Epstein-Barr virus-associated type of cytotoxic lymphoma thatpresents mainly in the nasal cavity and its vicinity. Very few cases of primary cutaneous extranodal natural killer/T-cell lymphoma have been reported till date. All the previously reported cases of primary cutaneous extranodalnatural killer/T-cell lymphoma presented as lesions resembling cellulitis, subcutaneous nodules or ulcers. We report a rare case which presented as erythematous and purpuric round patches on the arms and was finally diagnosed as primary cutaneous extranodalnatural killer/T-cell lymphoma, following a skin biopsy. The atypical patchy lesions presented a diagnostic challenge. We herein describe this clinically novel atypical patch-like presentation of primary cutaneous extranodalnatural killer/T-cell lymphoma together with the key histopathologic features and highlights of the previously reported cases.
Assuntos
Braço/patologia , Eritema/complicações , Eritema/diagnóstico , Células Matadoras Naturais/patologia , Linfoma Cutâneo de Células T/complicações , Linfoma Cutâneo de Células T/diagnóstico , Diagnóstico Diferencial , Eritema/imunologia , Humanos , Células Matadoras Naturais/imunologia , Linfoma Cutâneo de Células T/imunologia , Masculino , Pessoa de Meia-IdadeRESUMO
BACKGROUND: Leprosy continues to be present in certain regions throughout the world, and the dermatologist plays a central role in its diagnosis. Herein we report a case of tuberculoid leprosy that is atypical in terms of its linear presentation which appears to follow the lines of Blaschko. PATIENTS AND METHODS: A patient from Mayotte was referred to the neurological department for suspected tuberculoid leprosy. He was presenting a deficiency of the ulnar nerve together with neuronal hypertrophy and cutaneous involvement. Dermatological examination revealed linear hypo-aesthetic hypopigmented lesions on the arm and forearm. The atypical clinical presentation also suggested to us pigmented mosaicism or post-inflammatory pigmentation. The biopsy showed granulomatous epithelial dermatitis with perinervous involvement. Imaging examinations confirmed the presence of neuronal hypertrophy. A diagnosis of linear tuberculoid leprosy was made. DISCUSSION: This case illustrates the need to bear in mind a diagnosis of leprosy in the event of hypopigmented lesions, even where they are linear and of Blaschkoid appearance. Several potential hypotheses may account for this particular topographical pattern.
Assuntos
Padronização Corporal , Hanseníase Tuberculoide/diagnóstico , Braço/patologia , Biópsia , Comores/etnologia , Humanos , Hipertrofia , Hipopigmentação/etiologia , Hanseníase Tuberculoide/patologia , Masculino , Tuberculoma/patologia , Nervo Ulnar/patologia , Nervo Ulnar/fisiopatologia , Adulto JovemRESUMO
28 yr old male presented with asymptomatic nodules and few well to ill defined papules on ears, asymmetrical nerve enlargement and evanescent tender nodules on the extremities without any infiltration of the skin and madarosis. Slit skin smear done from normal skin was BI 6+. Skin biopsy showed features of lepromatous leprosy.
Assuntos
Hanseníase Virchowiana/diagnóstico , Adulto , Braço/microbiologia , Braço/patologia , Orelha Externa/microbiologia , Orelha Externa/patologia , Histiocitoma Fibroso Benigno/microbiologia , Histiocitoma Fibroso Benigno/patologia , Histocitoquímica , Humanos , Masculino , Pele/microbiologia , Pele/patologiaRESUMO
A man from the Dominican Republic presented with a white macula on the arm with sensibility loss. Skin biopsy showed a dermatitis with infiltration of dermal nerves. The diagnosis was indeterminate leprosy.